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br A br B br viability br Cell
2022-07-25
A B viability Cell 20 HFF Migrated cells (% of control) DMSO viability 40 Cell Invaded cells (% of control) Cortactin F-actin Merge anti-metastatic therapeutics through the structural modification of Benp. In conclusion, Benp will be a good molecular pr
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br TP INP mediated autophagy exacerbates cancer
2022-07-06
TP53INP2-mediated autophagy exacerbates cancer-induced muscle wasting Provided that cancer-induced muscle wasting could not be prevented by tissue-specific autophagy inhibition and that the formoterol-mediated muscle-sparing effect was not achieved by reduced autoph-agy flux, the next que
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br Corresponding author at Vanderbilt Epidemiology Center Vanderbilt Ingram Cancer
2022-05-30
Corresponding author at: Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, MCN B-2104, 1161 21st Avenue South, Nashville, TN, 37232-2400, USA. E-mail address: [email protected] (Q. Cai). smoking status can modify this potential a
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Joel E Segel et al br Kline RM
2022-05-25
Joel E. Segel et al 13. Kline RM, Bazell C, Smith E, Schumacher H, Rajkumar R, Conway PH. Centers for Medicare and Medicaid Services: using an episode-based payment model to improve oncology care. J Oncol Pract 2015; 11:114-6. 15. Alsirafy SA, Raheem AA, Al-Zahrani AS, et al. Emergency depa
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br CONCLUSIONS br Giving post SRS
2022-05-25
CONCLUSIONS Giving post-SRS systemic therapy to patients with Etoposide metas-tases and controlled extracranial disease may be an effective prophylaxis to reduce the risk of future brain relapse. The benefits of this approach on patients’ quality of life must be weighed against the costs of dru
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br MDSCs are a key
2022-05-23
MDSCs are a key immunosuppressive cell type and can suppress T cell-mediated anti-tumor immunity in breast cancer [32]. The sup-pressive abilities of MDSCs are closely related to their continuous ex-pression of ARG-1, which metabolizes l-arginine [33]. In addition, MDSCs are involved in angiogenes
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br Among NPs fabricated from different polymers human
2022-05-23
Among NPs fabricated from different polymers, human serum albu-min NPs have been considered because of some advantages such as high stability during storage and in vivo, excellent biocompatibility, biode-gradability, being non-toxic and non-antigenic [18]. Albumin has been known as a potent drug c
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br that NCTD induced apoptosis via both extrinsic and intrinsic
2022-05-22
that NCTD induced apoptosis via both extrinsic and intrinsic pathways by activation of the CD95 receptor system and many Caspases as well as the regulation of Bcl-2 protein family [46]. In our study, CNC as a mac-romolecular derivative could change nuclear morphology of tumor Cyclophosphamide and
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br In conclusion our study
2022-05-22
In conclusion, our study shows, both in vitro and in vivo, that overexpression of dupα7 in human NSCLC cell lines inhibits the onco-genic function of the tobacco-activated ancestral subunit that makes up α7-nAChR. Our finding is noteworthy, since to date few functions have been attributed to human
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br Curcumin reduces the CD
2022-05-20
Curcumin reduces the CD44+CD24− cell subpopulation of MCF-7 and MDA-MB-231 mammospheres mRNA expression is regulated by curcumin in mammospheres The mRNA levels of EMT markers, including E-cadherin, N-cad-herin, β-catenin, Vimentin, and Fibronectin were examined by RT-qPCR assay. Compared wi
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br Effect of miR PIC Nanocarrier on Bladder Tumor
2022-05-20
Effect of miR-143/PIC Nanocarrier on Bladder Tumor Growth in Xenografted Mouse Model Polyionic copolymer (PIC) was prepared by mixing miR-143s (aniomer) with poly (ethylene glycol)-b-poly (ornithine) (block catiomer) (Figure S4A)32. To evaluate the effect of Syn-miR-143s delivered by the PIC na
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b MD PhD Combined Degree Program
2022-05-17
b MD-PhD Combined Degree Program, University of Texas Medical Branch, Galveston, TX, 77555, USA c Institute for Cancer Genetics and Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, 10032, USA Keywords: Cancer metabolism One carbon
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br Dolfini D Gatta R Mantovani
2022-05-17
44. Dolfini D, Gatta R, Mantovani R. NF-Y and the transcriptional activation of CCAAT promoters. Crit Rev Biochem Mol Biol. 2012;47:29e49. Available online at ScienceDirect www.sciencedirect.com Research paper Analysis of diagnosis announcements in Abidjan pediatric oncology unit 2
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br Kennedy A Nag S Salem R Murthy
2022-05-17
[5] Kennedy A, Nag S, Salem R, Murthy R, McEwan AJ, Nutting C, et al. Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: 740 Y-P consensus panel report from the radioembolization brachy-therapy oncology consortium. Int J Radiat Oncol Biol Phys
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br PIK R phosphoinositide kinase
2022-05-17
PIK3R1 (phosphoinositide-3-kinase, regulatory subunit 1), is a component of PI3K signaling which is one the most frequently down-regulated pathways in several human cancers, including CRC. Somatic mutation of PIK3R1 was found to promote gliomagenesis [36]. The importance of PI3K signaling in vario
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